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Abstract #68939 Published in IGR 18-1

In vivo biometric evaluation of Schlemm's canal with spectral-domain optical coherence tomography in pseuduexfoliation glaucoma

Imamoglu S; Sevim MS; Alpogan O; Ercalik NY; Kumral ET; Pekel G; Bardak H
Acta Ophthalmologica 2016; 94: e688-e692


PURPOSE: To perform in vivo imaging of the Schlemm's canal (SC) with anterior segment spectral-domain optical coherence tomography [AS-spectral-domain (SD)-OCT] and also to measure its biometric parameters including the SC length and SC area in patients with pseudoexfoliation (PEX) glaucoma. METHODS: Forty-one consecutive patients with PEX glaucoma and 41 age- and sex-matched normal subjects were enrolled. All subjects underwent imaging with SD-OCT. The SC length and SC area were examined in the temporal sections and measured with customized software. RESULTS: The percentages of the temporal sections in which SC was observable were similar between the two groups. Mean SC length was found significantly shorter, and mean SC area was found significantly smaller in patients with PEX glaucoma than in controls (p = 0.044 and p = 0.036, respectively). Mean intra-ocular pressure (IOP) values were also similar between two groups. No significant correlations were found between SC measurements and IOP. CONCLUSIONS: Anterior segment spectral-domain optical coherence tomography offers non-invasive, in vivo measurement of the SC, and it could be used for investigating the SC changes in patients with PEX glaucoma.

Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey.

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Classification:

9.4.4.1 Exfoliation syndrome (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.4 Glaucomas associated with disorders of the lens)
6.9.2.1 Anterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)
2.5.2 Schlemms canal (Part of: 2 Anatomical structures in glaucoma > 2.5 Meshwork)



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