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Abstract #6907 Published in IGR 4-1
Lens fluorophotometry after trabeculectomy in primary open-angle glaucoma
Lazaro C; Benitez del Castillo JM; Castillo A; Garcia Feijoo J; Macias JM; Garcia Sanchez JOphthalmology 2002; 109:76-79
OBJECTIVE: To evaluate the loss of lens transparency incurred by patients undergoing trabeculectomy. DESIGN: A prospective cohort study. PARTICIPANTS AND CONTROLS: Data corresponding to 33 eyes of 33 consecutive patients with primary open-angle glaucoma (POAG) subjected to trabeculectomy (group 1) were compared with those corresponding to 12 eyes of 12 patients with POAG receiving topical antiglaucomatous treatment (group 2). INTERVENTION: Lens fluorophotometry was performed on the group 1 patients before and 12 months after surgery. In group 2, fluorophotometry was conducted at the onset of the study and at 12 months of follow-up. MAIN OUTCOME MEASURES: Starting and final lens autofluorescence and transmittance values corresponding to each subject group were compared. RESULTS: In group 1, starting and final autofluorescence was 556.3 ± 184.3 and 691.1 ± 179.3 Eq ng/ml, and starting and final transmittance was 0.78 ± 0.11 and 0.67 ± 0.14, respectively. Respective values for group 2 were 574.3 ± 94.8 and 595.2 ± 107.0 Eq ng/ml and 0.72 ± 0.17 and 0.71 ± 0.16. The mean change between final and initial autofluorescence was statistically different between groups (134.7 ± 123.7, group 1, 20.9 ± 25.1 Eq ng/ml, group 2; p < 0.001). Similarly, a significant difference (p < 0.001) in transmittance change was observed between the surgery and control groups (-0.11 ± 0.072, group 1; 0.02 ± 0.008, group 2). CONCLUSIONS: It was demonstrated by lens fluorophotometry that trabeculectomy in POAG leads to a loss in lens transparency.
Dr. C. Lazaro, Instituto de Investigaciones Oftalmologicas Ramon Castroviejo, Universidad Complutense, 28005 Madrid, Spain
Classification:
12.8.1 Without tube implant (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
12.8.11 Complications, endophthalmitis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
