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Abstract #69159 Published in IGR 18-1

Ocular Adnexal Lymphoma Presenting as Refractory Unilateral Open-angle Glaucoma

Sears NC; Singh A; Singh AD
Journal of Glaucoma 2016; 25: e741-e744


We report a single case of masquerade glaucoma caused by increased episcleral venous pressure from adnexal lymphoma. The patient presented as a referral for unilateral glaucoma with intraocular pressures (IOPs) consistently >40 mm Hg (right eye). We present data conclusively demonstrating extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue in the involved eye, and provide an account of the treatment of the tumor with sustained regression and complete resolution of his elevated IOP. We conclude with a discussion of the proposed mechanism. This case serves as a reminder that unilateral open-angle glaucoma can be a sign of indolent ocular adnexal lymphoma. The case also provides a useful model for increased IOP with orbital lesions.

Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH.

Full article

Classification:

10 Differential diagnosis e.g. anterior and posterior ischemic optic neuropathy
9.4.8 Glaucomas associated with intraocular tumors (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)



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