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Abstract #69409 Published in IGR 18-1
Repeatability of selective laser trabeculoplasty for open-angle glaucoma
Francis BA; Loewen N; Hong B; Dustin L; Kaplowitz K; Kinast R; Bacharach J; Radhakrishnan S; Iwach A; Rudavska L; Ichhpujani P; Katz LJBMC Ophthalmology 2016; 16: 128
See also comment(s) by Tony Realini •
BACKGROUND: To analyze the results of repeat selective laser trabeculoplasty (SLT). METHODS: Array INCLUSION CRITERIA: participants with primary or secondary open-angle glaucoma (excluding uveitic) who had undergone SLT 360° (SLT 1) with diminution of response over time followed by repeat SLT 360° (SLT 2). Six months of follow-up were required and at least 6 months in between SLT 1 and 2. The main outcome measures were IOP reduction at 6 and 12 months and a comparison of the response between SLT 1 and 2. RESULTS: One hundred thirty-seven patients met the inclusion criteria. If only one eye had repeat treatment, that eye was chosen; if both eyes qualified, one was chosen at random. The baseline intraocular pressure (IOP) for SLT 1 = 20.3+/- 5.2 mmHg and SLT 2 = 19.4 +/- 5.0 was reduced to 16.4 +/- 3.9 and 16.7 +/- 4.7 at 1 year, respectively (p < .001). Medication use was not significantly changed, and was 2.2 +/- 1.2 at baseline for SLT 1 and 2.1 +/- 1.3 for SLT 2, and at 1 year was 1.9 +/- 1.3 and 2.2 +/- 1.2, respectively. A subanalysis of 62 patients matched for equivalent baselines showed a baseline IOP = 18.7 +/- 3.8 for SLT 1 and 18.7 +/- 3.5 for SLT 2, reduced to 16.0 +/- 4.3 and 15.3 +/- 3.8 at 1 year (p < .001). CONCLUSION: Repeat SLT laser (360-degree treatment, followed by a loss of effect over time, then a second 360-degree treatment) in this population resulted in IOP lowering similar to that of the initial treatment.
Department of Ophthalmology, David Geffen School of Medicine at UCLA, Doheny Eye Institute, 800 Fairmount Avenue, Suite 215, Pasadena, Los Angeles, CA, 91105, USA. bfrancis@doheny.org.
Full articleClassification:
12.4 Laser trabeculoplasty and other laser treatment of the angle (Part of: 12 Surgical treatment)
