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Abstract #70312 Published in IGR 18-2
Late postoperative opacification of a hydrophilic-hydrophobic acrylic intraocular lens
Bompastor-Ramos P; Póvoa J; Lobo C; Rodriguez AE; Alió JL; Werner L; Murta JNJournal of Cataract and Refractive Surgery 2016; 42: 1324-1331
PURPOSE: To report late postoperative opacification of a model of hydrophilic-hydrophobic acrylic intraocular lens (IOL) as well as the clinical consequences and laboratory characteristics. SETTING: Department of Ophthalmology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal. DESIGN: Retrospective case series. METHODS: Medical records were reviewed of patients with Lentis LS-502-1 IOL opacification reporting visual loss who had IOL explantation between November 2013 and March 2015. Patients were identified in the emergency room or during regular follow-up visits. Explanted IOLs were analyzed at the Ophthalmic Explants Biobank, Vissum, Spain, or at the John A. Moran Eye Center, University of Utah, USA. RESULTS: Twenty opacified IOLs were explanted from 19 patients. The mean interval between cataract surgery and diagnosis of opacification was 29.15 months ± 9.57 (SD) (range 6 to 45 months). Opacification led to a statistically significant reduction in corrected distance visual acuity (mean 0.86 ± 0.76 logMAR; P < .001) and occurred in 5.1% of the hydrophilic-hydrophobic acrylic IOLs implanted at the department. The most frequently associated medical conditions were arterial hypertension, diabetes, and glaucoma. All IOLs but 1 had a similar pattern of opacification, with yellowish diffuse opacification uniformly distributed and calcium deposits on the surface and/or subsurface of the optic and haptics and within the IOL material. CONCLUSIONS: Opacification of the hydrophilic-hydrophobic acrylic IOL was found in a significant number of patients and had a significant effect on their vision. The opacification was attributed to primary calcification. FINANCIAL DISCLOSURE: None of the authors has a financial or proprietary interest in any material or method mentioned.
From the Department of Ophthalmology (Bompastor-Ramos, Póvoa, Lobo, Murta), Centro Hospitalar e Universitário de Coimbra, and the Faculty of Medicine (Lobo, Murta), University of Coimbra, Coimbra, Portugal; the Research and Development Department (Rodriguez, Alió), Ophthalmic Explants Biobank, Vissum Alicante, and the Division of Ophthalmology (Alió), Universidad Miguel Hernández, Alicante, Spain; the John A. Moran Eye Center (Werner), University of Utah, Salt Lake City, Utah, USA.
Full articleClassification:
9.4.11.2 Glaucomas in aphakia and pseudophakia (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.11 Glaucomas following intraocular surgery)
