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Abstract #70596 Published in IGR 18-2
Changes in Anterior Segment Morphology of Iris Bombe before and after Laser Peripheral Iridotomy in Patients with Uveitic Secondary Glaucoma
Ikegawa W; Suzuki T; Namiguchi K; Mizoue S; Shiraishi A; Ohashi YJournal of Ophthalmology 2016; 2016: 8496201
PURPOSE: To quantify changes in anterior segment (AS) parameters after laser peripheral iridotomy (LPI) using AS-optical coherence tomography (OCT) of iris bombe. METHOD: AS images of eight eyes were captured before and after iris bombe and more than 2 weeks after LPI (post-LPI) using AS-OCT. We compared the following AS parameters: anterior chamber depth (ACD), anterior chamber volume (ACV), iris curvature (IC), iris thickness at 500 μm from the scleral spur (IT-1) in the middle between the iris root and pupillary margin (IT-2) and 500 μm from the pupillary margin (IT-3) to the anterior chamber angle (ACA) (angle opening distance [AOD750]), and trabecular iris space area. RESULTS: Mean IT-1 and IT-3, but not IT-2, were lower after iris bombe (IT-1, P = 0.001; IT-2, P = 0.081; and IT-3, P = 0.001). There were no significant differences between ACD at pre-LPI and before iris bombe (P = 0.096). The mean ACV and AOD750 of iris bombe increased at post-LPI (ACV, P < 0.01, and AOD750, P < 0.05). The mean IT-1, IT-2, and IT-3 increased at post-LPI (all, P ≤ 0.01). IC decreased at post-LPI (P < 0.001), and ACD at post-LPI did not change. CONCLUSIONS: The iris extends and becomes thinner during iris bombe. LPI during bombe decreases the IC and increases the ACV and ACA.
Department of Ophthalmology, Graduate School of Medicine, Ehime University, Toon, Ehime 791-0295, Japan.
Full articleClassification:
9.4.6 Glaucomas associated with inflammation, uveitis (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
2.8 Iris (Part of: 2 Anatomical structures in glaucoma)
12.2 Laser iridotomy (Part of: 12 Surgical treatment)
