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Abstract #70716 Published in IGR 18-2
Uveitic Glaucoma: Long-term Clinical Outcome and Risk Factors for Progression
Sharon Y; Friling R; Luski M; Campoverde BQ; Amer R; Kramer MOcular Immunology and Inflammation 2016; 0: 1-8
PURPOSE: To study the long-term clinical outcomes of uveitic glaucoma and to identify risk factors for progression. METHODS: Retrospective study of uveitic glaucoma patients in two tertiary medical centers in 2003-2015. Patient- and disease-related data was retrieved. Clinical parameters and visual fields measured at predetermined time points were recorded. Outcome measures included maintaining intraocular pressure ≤21 mmHg and preserving visual fields. RESULTS: Included were 34 patients (53 eyes), with a mean follow-up of 7 years. Idiopathic anterior uveitis and open-angle glaucoma were most common. In total, 62% of eyes were steroid responders. Higher IOP was associated with posterior synechiae, peripheral-anterior synechiae, steroidal, and immunomodulatory therapy (p<0.05). Glaucomatous field defects developed in 49%, with most showing no progression, despite elevation of cup-to-disc ratio (p<0.05). CONCLUSIONS: Chronic severe uveitis, expressed by structural complications and immunomodulatory therapy, was associated with high IOP and the need for more IOP lowering medications, but was unrelated to glaucomatous damage.
a Department of Ophthalmology , Rabin Medical Center, Beilinson Hospital , Petach Tikva , Israel.
Full articleClassification:
9.4.6 Glaucomas associated with inflammation, uveitis (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
6.20 Progression (Part of: 6 Clinical examination methods)
