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Abstract #72632 Published in IGR 18-4
Relationship between intraocular pressure, anterior chamber depth and lens thickness in primary open-angle glaucoma patients
Adewara BA; Adegbehingbe BO; Onakpoya OH; Ihemedu CGInternational Ophthalmology 2018; 38: 541-547
INTRODUCTION: To investigate the relationship between intraocular pressure (IOP), anterior chamber depth (ACD) and lens thickness (LT) in primary open-angle glaucoma (POAG) patients and compare with age- and sex-matched controls. METHODS: A cross-sectional analytical study of 62 newly diagnosed POAG patients compared with 62 age- and sex-matched control subjects in a tertiary eye clinic. Socio-demographic data and ocular examinations were documented. IOP was measured using the Goldmann applanation tonometer. LT and ACD were measured using A-scan ultrasonography and the IOLMaster, respectively. Data were analyzed using SPSS version 19.0 and level of significance set at p value <0.05. RESULTS: In the glaucoma group and control groups, respectively, mean age was 60.3 ± 8.9 and 58.5 ± 8.1 years (p = 0.234), mean IOP was 28.27 ± 7.88 and 14.47 ± 2.60 mmHg (p < 0.001), mean ACD was 3.12 ± 0.27 and 3.15 ± 0.24 mm (p = 0.514), mean LT was 4.24 ± 0.46 and 4.23 ± 0.45 mm (p = 0.903), and mean ACD was shallower in females (p = 0.034) and (p = 0.001). In the glaucoma group, there was a positive correlation between IOP and ACD (r = 0.022, p = 0.864), but a negative correlation between IOP and LT (r = -0.04, p = 0.758) and ACD and LT (r = -0.058, p = 0.657). In the control group, there was a positive correlation between IOP and ACD (r = 0.141, p = 0.275), IOP and LT (r = 0.031, p = 0.811) and ACD and LT (r = 0.016, p = 0.901). CONCLUSION: ACD is shallower in females. There is no significant correlation between IOP and ACD or between IOP and LT in POAG as well as normal individuals.
Ophthalmology Department, College of Heath Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria. dr.bolajoko@yahoo.com.
Full articleClassification:
6.1.3 Factors affecting IOP (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)
2.4 Anterior chamber angle (Part of: 2 Anatomical structures in glaucoma)
2.10 Lens (Part of: 2 Anatomical structures in glaucoma)
