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Abstract #72642 Published in IGR 18-4
Monitoring daily intraocular pressure fluctuations with self-tonometry in healthy subjects
Quérat L; Chen EActa Ophthalmologica 2017; 95: 525-529
PURPOSE: To evaluate the accuracy of the intraocular pressure (IOP) measured by healthy subjects with icare(®) Home and to observe the IOP fluctuation and pattern of IOP fluctuation in healthy subjects over three consecutive days. METHODS: Sixty healthy subjects were recruited to the study. IOP was measured by the subjects themselves and by study staff using icare(®) Home tonometers on visits 1 and 2, as well as by study staff using Goldmann applanation tonometry (GAT). Furthermore, the subjects measured their IOP at home for three consecutive days. RESULTS: Twenty-three per cent of the study eyes were excluded in the statistical analysis due to dropout or non-compliance to the schedule. Approximately 70% of the icare(®) Home measurements were within 3 mmHg of the GAT measurements. Ten to 16% of the study eyes had IOP peaks outside office hours. Sixty-three per cent of the study eyes had different IOP patterns on consecutive days. CONCLUSION: Rebound self-tonometry appears to be accurate and could be used to monitor short- and long-term IOP variations. The difference between IOP patterns on consecutive days raises questions as to the certainty of a single IOP measurement as a measure of treatment effect.
Department of Clinical Neurosciences, Department of Anterior Segment Disorders, Glaucoma, Neuro-Ophthalmology and Oculoplastics (Clinic 1), St. Erik Eye Hospital, Karolinska Institutet, Stockholm, Sweden.
Full articleClassification:
6.1.2 Fluctuation, circadian rhythms (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)
6.1.1 Devices, techniques (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)