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Abstract #72726 Published in IGR 18-4
Differentiating Leber Hereditary Optic Neuropathy from Normal-Tension Glaucoma
Souto FM; de Vasconcellos JP; de Melo MB; Sartorato EL; Moura FCNeuro-Ophthalmology 2017; 41: 99-102
Glaucoma is a neurodegenerative disorder characterized by thinning of neuroretinal rim, enlarged cup-to-disc ratio (CDR) and visual field damage. Although raised intraocular pressure is main risk factor for development of glaucoma, it can occur with consistently normal measurements in the intraocular pressure as normal tension glaucoma (NTG). Enlargement of CDR is a classical sign of glaucoma, but it can also result from non-glaucomatous optic neuropathies such as Leber hereditary optic neuropathy (LHON). We describe a case of LHON with increased CDR, discuss its differential diagnosis with NTG and highlight the reasons for misdiagnoses between these two entities.
Department of Ophthalmology, Faculty of Medical Sciences, University of Campinas , Campinas, São Paulo, Brazil.
Full articleClassification:
10 Differential diagnosis e.g. anterior and posterior ischemic optic neuropathy
9.2.4 Normal pressure glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
