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Abstract #72861 Published in IGR 18-4
Preclinical imaging of iridocorneal angle and fundus using a modified integrated flexible handheld probe
Hong XJJ; Shinoj VK; Murukeshan VM; Baskaran M; Aung TJournal of medical imaging (Bellingham, Wash.) 2017; 4: 026001
A flexible handheld imaging probe consisting of a [Formula: see text] charge-coupled device camera, light-emitting diode light sources, and near-infrared laser source is designed and developed. The imaging probe is designed with specifications to capture the iridocorneal angle images and posterior segment images. Light propagation from the anterior chamber of the eye to the exterior is considered analytically using Snell's law. Imaging of the iridocorneal angle region and fundus is performed on ex vivo porcine samples and subsequently on small laboratory animals, such as the New Zealand white rabbit and nonhuman primate, in vivo. The integrated flexible handheld probe demonstrates high repeatability in iridocorneal angle and fundus documentation. The proposed concept and methodology are expected to find potential application in the diagnosis, prognosis, and management of glaucoma.
Nanyang Technological University, Centre for Optical and Laser Engineering, School of Mechanical and Aerospace Engineering, Singapore.
Full articleClassification:
3.13.4 Other (Part of: 3 Laboratory methods > 3.13 In vivo imaging)
2.4 Anterior chamber angle (Part of: 2 Anatomical structures in glaucoma)
