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Abstract #74412 Published in IGR 19-1

Intravitreal Injections of Bevacizumab: The Impact of Needle Size in Intraocular Pressure and Pain

Loureiro M; Matos R; Sepulveda P; Meira D
Journal of Current Glaucoma Practice 2017; 11: 38-41

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AIM: To compare the effect of 30-gauge vs 27-gauge needle size on intraocular pressure (IOP) rise and patients' pain experience after intravitreal injection (IVI) of bevacizumab. MATERIALS AND METHODS: Cross-sectional, randomized, double-armed study. Patients were randomized to IVI with 30-gauge or 27-gauge needle. The IOP was measured pre and post IVI. Patients' pain was graded using the visual analog scale (VAS). RESULTS: A total of 54 eyes were included. The IVI caused a significant IOP rise in both groups (p < 0.001). In the 30-gauge group, the mean pre- and postinjection IOP was 16.3 ± 3.6 mm Hg and 24.1 ± 9.0 mm Hg. The corresponding figures in the 27-gauge group were 18.0 ± 2.54 (p = 0.26) and 23.1 ± 7.5 mm Hg (p = 0.66). In the 30-gauge group, the mean VAS pain score was 3.2 ± 2.6 compared to 3.0 ± 2.5 in the 27-gauge group (p = 0.78). CONCLUSION: The IVI caused a significant rise in IOP after the injection, independently of the needle size used. The 27-gauge needle coursed with lower postinjection IOP without prejudice of the patient comfort. CLINICAL SIGNIFICANCE: The IVI with 27-gauge may be considered for glaucomatous eyes (higher risk eyes), for which IOP spikes are not recommended. HOW TO CITE THIS ARTICLE: Loureiro M, Matos R, Sepulveda P, Meira D. Intravitreal Injections of Bevacizumab: The Impact of Needle Size in Intraocular Pressure and Pain. J Curr Glaucoma Pract 2017;11(2):38-41.

Resident, Department of Ophthalmology, Centro Hospitalar de Vila Nova de Gaia/Espinho, Porto, Portugal.

Full article

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Classification:

9.4.5.5 Other (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.5 Glaucomas associated with disorders of the retina, choroid and vitreous)
11.15 Other drugs in relation to glaucoma (Part of: 11 Medical treatment)
6.1.3 Factors affecting IOP (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)

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