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Abstract #74530 Published in IGR 19-1
Are optic nerve heads of patients with helicobacter pylori infection more susceptible to glaucomatous damage?
Atilgan CU; Kosekahya P; Yozgat A; Sen E; Berker N; Caglayan M; Sendul SY; Altiparmak E; Yilmazbas PHelicobacter 2017; 22:
BACKGROUND: To compare retinal nerve fiber layer thicknesses (RNFLT) of patients with or without Helicobacter pylori infection and to reveal the possible RNFLT changes after H. pylori eradication. MATERIALS AND METHODS: Sixty-five eyes of 65 patients that tested positive for H. pylori (Group 1) and 48 eyes of 48 patients that tested negative for H. pylori (Group 2) were included. RNFLT analyses were performed with spectral-domain (SD) optical coherence tomography (OCT) in a total of five regions: the superior, inferior, nasal, and temporal quadrants and the average. Then, a comparison was made between groups. After H. pylori eradication in 38 patients, RNFLTs were compared with both pre-eradication values and Group 2. RESULTS: The groups were similar in terms of age and gender. Temporal quadrant RNFLT was thinner in Group 1 than in Group 2 (P=.02). After H. pylori eradication, RNFLTs did not differ from pre-eradication values in Group 1 (P>.05 for all), whereas temporal quadrant RNFLT after H. pylori eradication was thinner compared to Group 2 (P=.03). CONCLUSIONS: H. pylori may cause the localized defects on RNFL that are the early signs of glaucoma.
Ankara Ulucanlar Eye Training and Research Hospital, Altindag/Ankara, Turkey.
Full articleClassification:
9.4.15 Glaucoma in relation to systemic disease (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
2.14 Optic disc (Part of: 2 Anatomical structures in glaucoma)
6.9.2.2 Posterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)