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Abstract #75268 Published in IGR 19-2
Topographic Relationship Between Optic Disc Torsion and ß-Zone Peripapillary Atrophy in the Myopic Eyes of Young Patients With Glaucomatous-appearing Visual Field Defects
Lee J; Lee JE; Kwon J; Shin JW; Kook MSJournal of Glaucoma 2018; 27: 41-49
PURPOSE: The purpose of this study was to assess the topographic correlation between optic disc torsion (ODT) and beta-zone peripapillary atrophy (β-PPA) in young patients with myopia and glaucomatous-appearing visual field defects (VFDs). PATIENTS AND METHODS: We consecutively recruited 110 eyes of 110 young patients with myopia and glaucomatous-appearing VFDs. Retinal nerve fiber layer (RNFL) and macular ganglion cell inner plexiform layer (mGCIPL) thicknesses were measured to compare between the groups with different ODT directions. For evaluating topographic correlation, the direction and degree of ODT and the direction and angles of β-PPA and point of maximum radial extent (PMRE) of β-PPA were measured on fundus photographs. Multivariate logistic regression analysis was performed to determine the clinical factors associated with inferior ODT direction. The relationships between torsional degree and clinical variables were evaluated using linear regression analyses. RESULTS: Among the 110 eyes, 19 had superior ODT and 91 had inferior ODT. Compared with myopic eyes with superior ODT, those with inferior ODT showed less severity of glaucoma as determined by RNFL or mGCIPL thickness and had a longer axial length, greater amount of optic disc tilt, larger β-PPA angle, and higher ratio of β-PPA area and disc area. ODT direction was significantly associated with the locations of β-PPA and PMRE. Torsional degree was significantly correlated with the β-PPA angle. CONCLUSIONS: ODT direction showed a significant association with the locations of β-PPA and PMRE of β-PPA. Torsional degree was correlated with the β-PPA angle in the myopic eyes of young patients with glaucomatous-appearing VFDs.
Department of Ophthalmology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.
Full articleClassification:
8.1 Myopia (Part of: 8 Refractive errors in relation to glaucoma)
6.6.2 Automated (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)
