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Abstract #75316 Published in IGR 19-2
Glaucoma-associated corneal endothelial cell damage: A review
Janson BJ; Alward WL; Kwon YH; Bettis DI; Fingert JH; Provencher LM; Goins KM; Wagoner MD; Greiner MASurvey of Ophthalmology 2017; 0:
The corneal endothelium is critical in maintaining a healthy and clear cornea. Corneal endothelial cells have a significant reserve function, but preservation of these cells is paramount as they have limited regenerative capacity. Glaucoma is a prevalent disease, and damage to the corneal endothelium may be caused by the disease process itself as well as by its treatment. The mechanisms involved in glaucoma-associated damage to the corneal endothelium need further investigation. Understanding how glaucoma and glaucoma surgery impact the endothelium is important for protecting corneal clarity and visual acuity in all glaucoma patients, including those undergoing corneal transplant. We will discuss a range of identified factors that may impact corneal endothelial cell health in glaucoma, including intraocular pressure, glaucoma medications, surgical glaucoma management, mechanical forces, and alterations in the aqueous environment.
Department of Ophthalmology and Visual Sciences, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
Full articleClassification:
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)
