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Abstract #77145 Published in IGR 19-3
Influence of Socio-demographic Factors on Disease Characteristics and Vision-related Quality of Life in Primary Open Angle Glaucoma Patients. The Italian Primary Open Angle Glaucoma Study (IPOAGS)
Riva I; Legramandi L; Katsanos A; Oddone F; Rulli E; Roberti G; Quaranta L;Journal of Glaucoma 2018; 0:
PURPOSE: To evaluate the potential association between socio-demographic factors with clinical characteristics, vision-related quality of life and glaucoma-related symptoms scores in a large cohort of primary open angle glaucoma (POAG) patients. MATERIAL AND METHODS: Multicenter, cross-sectional study involving academic and non-academic centers. Previously diagnosed POAG patients aged >18 years were enrolled. At baseline, information on demographic characteristics, social, medical and ocular history, clinical presentation and treatments was collected. Vision-related quality of life was evaluated by means of the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25), while glaucoma-related symptoms were evaluated using the Glaucoma Symptom Scale (GSS) questionnaire. The associations between socio-demographic factors with clinical characteristics (mean deviation (MD), pattern standard deviation (PSD), best corrected visual acuity (BCVA)), NEI-VFQ-25 and GSS scores were evaluated by means of univariate and multivariate general linear models. RESULTS: A total of 3227 patients were enrolled. Older age and male sex were significantly associated with lower MD (P<0.01) and higher PSD (P<0.01), whereas older age was associated with lower BCVA (P<0.01). The composite GSS score was related to age (P=0.02), sex (P<0.01), employment (P=0.01) and profession (P=0.04), while the total NEI-VFQ-25 score was associated with sex (P<0.01), marital status (P=0.02) and employment (P=0.02). CONCLUSIONS: Age and sex were significantly associated with almost all indicators of glaucoma severity at baseline. Other variables, such as employment, profession and marital status were significantly associated with vision-related quality of life scores.
IRCCS - Fondazione G.B. Bietti, Rome, Italy.
Full articleClassification:
1.4 Quality of life (Part of: 1 General aspects)
15 Miscellaneous
