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(23)

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Abstract #78138 Published in IGR 19-4

Iris melanoma presenting as childhood glaucoma

Gapsis BC; Warren NA; Nutaitis MJ; Bonaparte LA; Cooper SL; Ashenafi M; Grossniklaus HE; Magrath GN
American journal of ophthalmology case reports 2018; 11: 56-60

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PURPOSE: To describe the natural history and management of a rare case of iris melanoma in a pediatric patient. OBSERVATIONS: A Caucasian female presented with left pupillary abnormalities at age 7, progressive iris changes at age 9, and markedly elevated intraocular pressure with advanced optic nerve cupping at 11 years of age. She was found to have a pigmented lesion overlying her iris and invading her angle. Trans-corneal fine needle aspirate biopsy demonstrated malignant melanoma of the iris. The patient subsequently underwent Iodine-125 plaque brachytherapy for the tumor. CONCLUSIONS: and Importance: Early identification and treatment of iris melanoma may be associated with decreased risk of local progression and metastatic disease. Treatment of glaucoma in conjunction with uveal melanoma is complicated by tumor specific considerations, including treatment of the tumor and prevention of metastasis.

Department of Ophthalmology, Storm Eye Institute, Medical University of South Carolina, Charleston, SC, USA.

Full article

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Classification:

10 Differential diagnosis e.g. anterior and posterior ischemic optic neuropathy
9.4.8 Glaucomas associated with intraocular tumors (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
9.1.2 Juvenile glaucoma (Part of: 9 Clinical forms of glaucomas > 9.1 Developmental glaucomas)
2.8 Iris (Part of: 2 Anatomical structures in glaucoma)

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