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Abstract #78233 Published in IGR 19-4
Comparison of Intraocular Pressure Changes during the Water Drinking Test between Different Fluid Volumes in Patients with Primary Open Angle Glaucoma
Susanna CN; Susanna R; Hatanaka M; Susanna BN; Susanna FN; De Moraes CGJournal of Glaucoma 2018; 0:
PURPOSE: To compare the intraocular pressure (IOP) response during the water drinking test (WDT) performed with 800▒mL, 1000▒mL and 10▒mL/kg of body weight and to test its relationship with body mass index (BMI). METHODS: In this prospective, observer-masked, observational study, treated patients with primary open angle glaucoma were evaluated. In Group I, 29 consecutive patients with body weight ≤60▒Kg underwent an 800▒mL fluid challenge followed by a second WDT session with 10▒mL/kg of body weight no longer than four months apart. Group II included 30 consecutive patients with body weight >60▒Kg who underwent a 1000▒mL fluid challenge followed by an 800▒mL test no longer than four months apart. IOP was measured before (baseline) and after water ingestion every 15 minutes for 45 minutes. RESULTS: In Group I, there was no significant difference in baseline or peak IOP between 800▒mL and 10▒mL/kg of body weight tests (P=0.12 and 0.56, respectively). However, 10▒mL/Kg tended to lead to consistently lower IOP values and a biased response in eyes with higher IOP. In Group II, there was also no significant difference in baseline or peak IOP between 800▒mL and 1000▒mL tests (P=0.26 and 0.72, respectively). No biased response was observed in this group. There was no significant association between IOP peak and BMI with 800▒mL (P= 0.18), 10▒mL/kg (P= 0.29), or 1000▒mL (P= 0.34). CONCLUSIONS: There was overall good agreement between WDT results with different fluid volumes. BMI does not affect the IOP response to the volume loads tested in this study.
Faculty of Medicine of ABC, Sao Paulo, Brazil.
Full articleClassification:
6.13 Provocative tests (Part of: 6 Clinical examination methods)