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PURPOSE: To determine the relationship between macular thickness and peripapillary retinal nerve fiber layer (RNFLp) thickness in different stages of primary open-angle glaucoma (POAG). METHODS: Ninety prospectively selected patients with different stage POAG underwent spectral domain optical coherence tomography (SD-OCT) to determine macular and RNFLp thicknesses in different regions and sectors respectively. Correlations were then established through Pearson's correlation coefficient between RNFLp and macular thicknesses in the different disease stages. RESULTS: Greatest correlation was observed between the inferior RNFLp sector and the internal inferior macula both in the whole patient population and in the subset of patients with incipient glaucoma. CONCLUSIONS: When the optic nerve disc is affected by another condition, macular thickness determination may help detect POAG and monitor its progression.
Hospital Universitario Rey Juan Carlos, Madrid, Spain. Electronic address: m.sanchezpulgarin@gmail.com.
Full article6.9.2.2 Posterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)
2.13 Retina and retinal nerve fibre layer (Part of: 2 Anatomical structures in glaucoma)