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Abstract #79385 Published in IGR 20-2
Assessment of Schlemm's canal in acute primary angle closure: an anterior segment optical coherence tomography study
Mansoori T; Reddy AA; Tumati NC; Balakrishna NInternational Ophthalmology 2019; 39: 2171-2177
PURPOSE: To image and quantitatively evaluate the Schlemm's canal (SC) dimensions in the eyes with acute primary angle closure (APAC) with anterior segment optical coherence tomography (AS-OCT), and compare it with the SC measurements taken after the control of intraocular pressure (IOP) and in the normal age-matched controls. MATERIALS AND METHODS: Seventeen eyes of 14 patients with the newly diagnosed APAC and 59 age-matched normal subjects underwent AS-OCT to image SC. SC cross-sectional area, SC meridional and coronal diameters were measured in the temporal and nasal regions at 3 and 9 o'clock position. After laser iridotomy and control of the IOP, all SC parameters were measured again at a week later, in APAC eyes. Intrasession intraobserver reliability of the SC measurements was assessed with intraclass correlation coefficient. RESULTS: Mean SC-SCA (10,600 ± 2691 µm), SC meridional (682 ± 125 µm) and coronal diameters (21.2 ± 8.2 µm) showed a significant increase in the APAC eyes at presentation, when compared to the SC parameters measured at a week later (6499 ± 1754 µm, 450 ± 169 µm and 15.75 ± 8.6 µm, p = < 0.0001, < 0.0001 and 0.01, respectively) and in the normal controls (7192 ± 1022 µm, 499.2 ± 179.8 µm, 15.43 ± 4.35 µm, p = 0.02, < 0.0001, 0.01, respectively). There was no difference in the measured SC parameters between the normal controls and APAC eyes, when the parameters were measured at a week, after resolution of the acute attack (all p > 0.05). CONCLUSION: A significant expansion of SC was observed in the APAC eyes at presentation, when compared to the normal controls and after the acute attack resolved. SC parameters may provide a useful research tool for evaluating morphological changes in the SC in APAC eyes, during an acute attack.
Sita Lakshmi Glaucoma Center, Anand Eye Institute, 7-147/1, Nagendra Nagar, Habsiguda, Hyderabad, Telangana, India. tarannummansoori@yahoo.com.
Full articleClassification:
9.3.1 Acute primary angle closure glaucoma (pupillary block) (Part of: 9 Clinical forms of glaucomas > 9.3 Primary angle closure glaucomas)
2.5.2 Schlemms canal (Part of: 2 Anatomical structures in glaucoma > 2.5 Meshwork)
