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Abstract #79558 Published in IGR 20-2

Acute narrow-angle glaucoma induced by topiramate with acute myopia and macular striae: A case report

Sierra-Rodríguez MA; Rodríguez-Vicente L; Chavarri-García JJ; Del Río-Mayor JL
Archivos de la Sociedad Española de Oftalmologia 2019; 94: 130-133

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We report the case of a 29-year-old epileptic woman who had been on treatment with topiramate 25mg/day for 9 days. She was referred to the Emergency Department due to reduction in far visual acuity (VA) after increasing the dose to 50mg/day two days before. The ocular examination showed bilateral acute angle closure glaucoma (AACG) and macular striae in both eyes (AO) observed by Retinography and Optical Coherence Tomography (OCT). The AACG is a well-known side effect of topiramate, but the macular striae rarely accompanies it. Although macular striae have been previously described in other cases, very few document those using retinography and OCT images. Therefore, it is important to differentiate a case of AACG induced by topiramate from a case of primary AACG, since they differ in their clinical presentation, mechanism of action, and treatment. Mismanagement can have potentially serious consequences.

Servicio de Oftalmología, Hospital San Pedro, Logroño, La Rioja, España. Electronic address: sffera@hotmail.com.

Full article

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Classification:

9.3.1 Acute primary angle closure glaucoma (pupillary block) (Part of: 9 Clinical forms of glaucomas > 9.3 Primary angle closure glaucomas)
8.1 Myopia (Part of: 8 Refractive errors in relation to glaucoma)
2.13 Retina and retinal nerve fibre layer (Part of: 2 Anatomical structures in glaucoma)

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