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AIM: To evaluate and compare the quality of life of patients submitted to XEN implant or trabeculectomy and the relationship with potentially involved variables. METHODS: A cross-sectional study of patients with advanced open-angle glaucoma who underwent implantation of XEN (group 1) and trabeculectomy (group 2) between October 2015 and February 2017. The studied variables were: age, gender, follow-up time, need of topical anti-hypertensive therapy, visual acuity and intraocular pressure (IOP). The quantification of the quality of life was attained through the Glaucoma Symptom Scale (GSS) questionnaire. RESULTS: Totally 34 eyes (34 patients) were included, 17 in each group. The mean GSS scores for group 1 were 42.6±6.8 (median, 47; p25, 36.5; p75, 48.5) and for group 2 it was 41.6±7.0 (median, 43; p25, 36.5; p75, 47.0; =0.34). There was a strong negative correlation between the need for topical anti-hypertensive drugs and the GSS result in both groups (=-0.88, <0.01, =-0.59, =0.01, respectively) and a moderate negative correlation with IOP in group 1 (=-0.50, =0.03). CONCLUSION: The analysis demonstrates the non-inferiority of medium-term quality of life of one group in relation to the other (XEN implant and trabeculectomy). The number of topical anti-hypertensive drugs and IOP negatively influenced the quality of life.
Ophthalmology Department, Central Lisbon Hospital Center, Lisbon 1169050, Portugal.
Full article1.4 Quality of life (Part of: 1 General aspects)
12.8.2 With tube implant or other drainage devices (Part of: 12 Surgical treatment > 12.8 Filtering surgery)