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Abstract #8062 Published in IGR 4-3

The influence of nitric synthase inhibitor (L-NAME) on the intraocular pressure in endotoxin induced uveitis in rats

Szymaniec S; Misiuk-Hojlo M
Klinika Oczna 2002; 104: 87-88


The authors studied the influence of the nitric synthase inhibitor (L-NAME) on the induction of uveitis in Wistar rats. The inflammation was induced by a footpad injection of endotoxin in the rats. The clinical signs were evaluated with a slit-lamp, the intraocular pressure (IOP) was measured using a TonoPen tonometer. The authors showed that, in endotoxin-induced uveitis, IOP elevation was observed and that L-NAME application reduced the inflammation and the level of the IOP. LA: Polish

S. Szymaniec, MD, Zakladu Terapii Doswiadczalnej Instytutu Immunologii i Terapii Doswiadczalnej Polskiej Akademii Nauk, Wroclawiu, Poland


Classification:

11.14 Investigational drugs; pharmacological experiments (Part of: 11 Medical treatment)



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