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Abstract #80820 Published in IGR 20-3

Retinal nerve fiber layer thickness in children with primary congenital glaucoma measured by spectral domain optical coherence tomography

Perucho-González L; Martínez de la Casa JM; Sáenz-Francés F; Morales-Fernandez L; Méndez-Hernández CD; Sánchez-Jean R; García-Feijoó J
Journal of AAPOS 2019; 23: 94.e1-94.e4


PURPOSE: To evaluate retinal nerve fiber layer (RNFL) thickness using spectral domain optical coherence tomography (SD-OCT) in a population of children diagnosed with primary congenital glaucoma (PCG). METHODS: In this cross-sectional study, 59 eyes of 59 children diagnosed with PCG and 87 eyes of 87 healthy children were evaluated by SD-OCT to measure the RNFL. The global average peripapillary RNFL thickness and sectional RNFL thickness were evaluated in both groups. Differences in global average and sectional thickness were analyzed. RESULTS: Mean age in the PCG group was 9.61 ± 3.23 years; in the control group, 8.47 ± 2.99 years (P = 0.0516). There were statistically significant differences (P < 0.007) in all sectors between both groups. CONCLUSIONS: SD-OCT is a promising tool for evaluating the eyes of children diagnosed with PCG. Future research should examine the test-retest variability of SD-OCT parameters and their ability to diagnose progression in these children.

Ophthalmology Service, Institute of Sanitary Research of the San Carlos Clinical Hospital, Madrid, Spain; Glaucoma Department, Institution of Sanitary Research of the San Carlos Clinical Hospital, Madrid, Spain. Electronic address: luciaperuchogonz@gmail.com.

Full article

Classification:

9.1.1 Congenital glaucoma, Buphthalmos (Part of: 9 Clinical forms of glaucomas > 9.1 Developmental glaucomas)
6.9.2.2 Posterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)



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