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Pseudopemphigoid is a chronic disease that causes progressive conjunctival scarring, up to symplepharon formation. Phenotypically, it cannot be distinguished from true mucous membrane pemphigoid with ocular involvement. Possible triggers are ocular surface disorders and/or their therapy. About 50% of all affected patients are glaucoma patients treated with topical antiglaucomatous therapy. Lack of signs of systemic disease, unilateral findings and/or a positive history of glaucoma may be indicative of a pseudopemphigoid. In this review, the two entities will be compared and the diagnostic as well as the therapeutic approach for suspected pseudopemphigoid under topical glaucoma therapy will be presented.
Klinik für Augenheilkunde, Universitätsklinikum Düsseldorf, Düsseldorf.
Full article2.1 Conjunctiva (Part of: 2 Anatomical structures in glaucoma)
11.1 General management, indication (Part of: 11 Medical treatment)