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1 General aspects (0)   1.1 Epidemiology (5)   1.2 Population genetics (15)   1.3 Pathogenesis (6)   1.4 Quality of life (5)   1.5 Glaucomas as cause of blindness (0)   1.6 Prevention and screening (5) 2 Anatomical structures in glaucoma (0)   2.1 Conjunctiva (2)   2.2 Cornea (3)   2.3 Sclera (0)   2.4 Anterior chamber angle (0)   2.5 Meshwork (16)     2.5.1 Trabecular meshwork (0)     2.5.2 Schlemms canal (0)     2.5.3 Scleral outlet channels (0)   2.6 Aqueous humor dynamics (5)     2.6.1 Production (0)     2.6.2 Outflow (0)       2.6.2.1 Trabecular meshwork (0)       2.6.2.2 Uveoscleral (0)     2.6.3 Compostion (0)   2.7 Episcleral veins and venous pressure (0)   2.8 Iris (0)   2.9 Ciliary body (0)   2.10 Lens (0)   2.11 Vitreous body (1)   2.12 Choroid, peripapillary choroid, peripapillary atrophy (1)   2.13 Retina and retinal nerve fibre layer (14)   2.14 Optic disc (16)   2.15 Optic nerve (0)   2.16 Chiasma and retrochiasmal central nervous system (0)   2.17 Stem cells (0)   2.20 Other (0) 3 Laboratory methods (9)   3.1 Microscopy (0)   3.2 Electron microscopy (3)   3.3 Immunohistochemistry (1)   3.4 Molecular genetics (1)     3.4.1 Linkage studies (0)     3.4.2 Gene studies (0)   3.5 Molecular biology incl. 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    9.4.1 Steroid-induced glaucoma (2)     9.4.2 Glaucomas associated with disorders of the cornea, conjunctiva, sclera (0)       9.4.2.1 Iridocorneal endothelial syndrome (ICE, incl. irisatrophy) (0)       9.4.2.2 Posterior polymorphous dystrophy (0)       9.4.2.3 Fuchs' endothelial dystrophy (0)       9.4.2.5 Other (0)     9.4.3 Glaucomas associated with disorders of the iris and ciliary body (0)       9.4.3.1 Pigmentary glaucoma (0)       9.4.3.5 Other (0)     9.4.4 Glaucomas associated with disorders of the lens (1)       9.4.4.1 Exfoliation syndrome (7)       9.4.4.2 Glaucomas associated with cataracts (0)       9.4.4.3 Glaucomas associated with lens dislocation (0)       9.4.4.5 Other (0)     9.4.5 Glaucomas associated with disorders of the retina, choroid and vitreous (0)       9.4.5.1 Neovascular glaucoma (3)       9.4.5.5 Other (0)     9.4.6 Glaucomas associated with inflammation, uveitis (5)     9.4.7 Glaucomas associated with ocular trauma (0)     9.4.8 Glaucomas associated with intraocular tumors (0)     9.4.9 Glaucomas associated with elevated episcleral venous pressure (0)       9.4.10 Glaucomas associated with hemorrhage (0)     9.4.11 Glaucomas following intraocular surgery (0)       9.4.11.1 Ciliary block (malignant) glaucoma (0)       9.4.11.2 Glaucomas in aphakia and pseudophakia (0)       9.4.11.3 Epithelial, fibrous, and endothelial proliferation (0)       9.4.11.4 Glaucomas associated with corneal surgery (2)       9.4.11.5 Glaucomas associated with vitreoretinal surgery (3)     9.4.15 Glaucoma in relation to systemic disease (6)     9.4.20 Other (0) 10 Differential diagnosis e.g. anterior and posterior ischemic optic neuropathy (7) 11 Medical treatment (0)   11.1 General management, indication (9)   11.2 Cholinergic drugs (0)   11.3 Adrenergic drugs (0)     11.3.1 Epinephrine (0)     11.3.2 Thymoxamine, dapiprazole (0)     11.3.3 Apraclonidine, brimonidine (6)     11.3.4 Betablocker (16)     11.3.5 Other (0)   11.4 Prostaglandins (24)   11.5 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tube implant (6)     12.8.2 With tube implant or other drainage devices (9)     12.8.3 Non-perforating (6)     12.8.4 Using laser (1)     12.8.5 Other (0)     12.8.10 Woundhealing antifibrosis (7)     12.8.11 Complications, endophthalmitis (8)   12.9 Trabeculotomy, goniotomy (3)   12.10 Cyclodestruction (4)   12.11 Cyclodialysis (0)   12.12 Cataract extraction (0)     12.12.1 Intracapsular (0)     12.12.2 Extracapsular (1)     12.12.3 Phacoemulsification (9)   12.14 Combined cataract extraction and glaucoma surgery (0)     12.14.1 Intracapsular (0)     12.14.2 Extracapsular (1)     12.14.3 Phacoemulsification (9)   12.15 Capsulotomy (0)   12.16 Vitrectomy (0)   12.17 Anesthesia (6)   12.20 Other (4) 13 Therapeutic prognosis and outcome (0)   13.1 Prognostic factors (0)   13.2 Outcome (0)     13.2.1 IOP (0)     13.2.2 Visual field (0)       13.2.2.1 Progression (0)       13.2.2.2 Improvement (0)     13.2.3 Other (0) 14 Costing studies; pharmacoeconomics (4) 15 Miscellaneous (4)

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Abstract #8174 Published in IGR 4-3

Optic nerve disc in unilateral myopia in children

Koraszewska-Matuszewska B; Samochowiec-Donocik E; Pieczara E; Filipek E
Klinika Oczna 2002; 104: 119-121

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PURPOSE: The evaluation of biomorphometric parameters of the optic nerve head of eyes with myopic anisometropia, to see if similar glaucoma changes as those described in adults were present. MATERIAL AND METHODS: Seventeen children (14 girls and three boys), aged from seven to 18 years (mean, 12.6 years) with unilateral myopia with a mean value of 8.6 D. The parameters of the optic nerve disc were: total contour area (TCA), cup/disc ratio (C/D), neuroretinal rim area (Rim), volume of neuroretinal rim (Vol A), cup volume (Vol B), maximum slope (MSL), and average slope angle (ASL), were examined using a TopSS laser scanning ophthalmoscope (Laser Diagnostic Technologies Inc). The group 1 consisted of myopic eyes, and group 2 of emmetropic eyes of the same children. RESULTS: Refraction in group 1 ranged from -4.5 to -12 D, mean -8.6 D, and in group 2 from 0 to + 1.0 D, mean 0.07 D. The mean axial length of eyeballs was 25.57 SD 1.9 mm in group 1 and 22.47 SD 1.09 mm in group 2; the difference being significant. There was not statistically significant difference between TCA in group 1 (mean 1.19 SD 0.75 mm²) and group 2 (mean 2.13 SD 0.49 mm²). Mean C/D ratio and cup volume were significantly smaller in myopic (C/D 0.23 SD 0.16 Vol B -0.06 SD 0.05) than in emmetropic (C/D 0.33 SD 0.11 mm³, Vol B -0.18 SD 0.14 mm³) eyes. CONCLUSIONS: Optic nerve disc images in myopic and glaucomatous eyes in children are different. Smaller optic disc cup in myopic than in emmetropic eyes can show that children's myopic eyeballs were enlarged without nerve fibers atrophy. LA: Polish

B. Koraszewska-Matuszewska, MD, Katedry i Kliniki Okulistyki Dzieciecej Slaskiej Akademii Medycznej, Katowicach, Poland

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Classification:

2.14 Optic disc (Part of: 2 Anatomical structures in glaucoma)
8.1 Myopia (Part of: 8 Refractive errors in relation to glaucoma)

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