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Abstract #82213 Published in IGR 20-4
Advances in diagnostic applications for monitoring intraocular pressure in Glaucoma: A review
Sanchez I; Martin RJournal of optometry 2019; 12: 211-221
Continuous intraocular pressure (IOP) monitoring for improving glaucoma diagnosis and treatment has remained a challenge for the past 60 years because glaucoma is the second leading cause of irreversible blindness worldwide. Several devices with different measurement principles and recently developed biosensors with semiconductor materials offer exciting properties. However, none of these devices for continuous IOP monitoring have been fully integrated into clinical practice, primarily due to technical problems. This review summarizes state-of-the-art biosensors developed for IOP monitoring by explaining their basic functions and applications, the main technology (pressure transductors, piezoresistive sensors, capacitive sensors, and resonant sensors), measurement approach (noninvasive, minimally invasive or invasive (surgically implantable)), and telemetry characteristics. To provide updated information for clinicians and researchers, we also describe the advantages and limitations of the application of these new sensors to eye care management. Despite significant improvements in IOP biosensor technology, the accuracy of their measurements must be improved to obtain a clear equivalence with actual IOP (measured in units of mmHg) to facilitate their clinical application. In addition, telemetry systems may be simplified to prevent adverse outcomes for patients and to guarantee the safety of stored data.
Universidad de Valladolid, Departamento de Física Teórica, Atómica y Óptica, Paseo de Belén, 7, Campus Miguel Delibes, Valladolid 47011, Spain; Universidad de Valladolid, Instituto Universitario de Oftalmobiología Aplicada (IOBA), Paseo de Belén, 17, Campus Miguel Delibes, Valladolid 47011, Spain; Optometry Research Group, IOBA Eye Institute, School of Optometry, University of Valladolid, Valladolid 47011, Spain. Electronic address: isanchezp@ioba.med.uva.es.
Full articleClassification:
6.1.1 Devices, techniques (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)
6.19 Telemedicine (Part of: 6 Clinical examination methods)