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Abstract #8235 Published in IGR 4-3
The influence of central corneal thickness and corneal curvature and axial length on the measurement of intraocular pressure
Li Q; Li M; Fan Z; Wang NEye Science 2002; 18: 176-180
PURPOSE: To examine the influence of central corneal thickness (CCT), corneal curvature (CC), and axial length (AL) on intraocular pressure (IOP). METHODS: Eighty-one clinically normal eyes were included in the study. IOP, CCT, CC, and AL were measured using a Goldmann applanation tonometer, optical pachymeter, keratometer, and A-scan ultrasound biometer, respectively, in all subjects. RESULTS: A highly significant positive correlation was identified between IOP and CCT. Linear regression analysis suggests that an increase in CCT of 0.010 mm is associated with a 4.946 mmHg increment in IOP. No significant positive correlation was identified between IOP and CC. P values are 0.724 and 0.414, respectively, for vertical and horizontal readings. A paradoxically reversed correlation was present between IOP and axial length. CONCLUSION: Corneal thickness is a very important confounding factor in the measurement of IOP, which warrants further attention in clinical practice.
L. Qing, MD, #54 Xian Lie Nan Road, Guangzhou, China 510060. wningli@21cn.com
Classification:
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)
6.1 Intraocular pressure measurement; factors affecting IOP (Part of: 6 Clinical examination methods)
6.12 Ultrasonography and ultrasound biomicroscopy (Part of: 6 Clinical examination methods)
