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1 General aspects (1)   1.1 Epidemiology (14)   1.2 Population genetics (2)   1.3 Pathogenesis (1)   1.4 Quality of life (20)   1.5 Glaucomas as cause of blindness (8)   1.6 Prevention and screening (13) 2 Anatomical structures in glaucoma (0)   2.1 Conjunctiva (10)   2.2 Cornea (23)   2.3 Sclera (16)   2.4 Anterior chamber angle (7)   2.5 Meshwork (0)     2.5.1 Trabecular meshwork (15)     2.5.2 Schlemms canal (1)     2.5.3 Scleral outlet channels (1)   2.6 Aqueous humor dynamics (0)     2.6.1 Production (0)     2.6.2 Outflow (1)       2.6.2.1 Trabecular meshwork (4)       2.6.2.2 Uveoscleral (1)     2.6.3 Compostion (6)   2.7 Episcleral veins and venous pressure (2)   2.8 Iris (6)   2.9 Ciliary body (0)   2.10 Lens (0)   2.11 Vitreous body (0)   2.12 Choroid, peripapillary choroid, peripapillary atrophy (18)   2.13 Retina and retinal nerve fibre layer (37)   2.14 Optic disc (42)   2.15 Optic nerve (2)   2.16 Chiasma and retrochiasmal central nervous system (13)   2.17 Stem cells (5)   2.20 Other (0) 3 Laboratory methods (0)   3.1 Microscopy (0)   3.2 Electron microscopy (2)   3.3 Immunohistochemistry (2)   3.4 Molecular genetics (0)     3.4.1 Linkage studies (0)     3.4.2 Gene studies (30)   3.5 Molecular biology incl. 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Abstract #82735 Published in IGR 20-4

Neutrophil-To-Lymphocyte Ratio as a Potential Biomarker of Neovascular Glaucoma

Zhang A; Ning L; Han J; Ma Y; Cao W; Sun X; Li S
Ocular Immunology and Inflammation 2019; 0: 1-8

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: To evaluate blood count-derived inflammation indexes as a detection or predictive marker for neovascular glaucoma (NVG) secondary to retinal vein occlusion (RVO) and diabetic retinopathy (DR).: This was a retrospective, case-control study design. The level of white blood cell (WBC), neutrophil (N), neutrophil/lymphocyte ratio (NLR), and lymphocyte/monocyte ratio (LMR) were evaluated in NVG patients secondary to RVO or DR.: A significant difference was found in those biomarkers between control group and NVG secondary to RVO or DR. Logistic regression analysis revealed these indexes were associated with the risk of NVG in DR and RVO patients. Multiple linear regression analysis showed a significant correlation between NLR and visual fields mean deviation in the NVG-RVO group.: This study indicated that WBC, N, NLR, and LMR were related to NVG, and NLR may be useful as an potential inflammation indicating the risk and severity for NVG secondary to RVO.

Department of Clinical Laboratory, Eye & ENT Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

Full article

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Classification:

9.4.5.1 Neovascular glaucoma (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.5 Glaucomas associated with disorders of the retina, choroid and vitreous)
9.4.15 Glaucoma in relation to systemic disease (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)

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