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Abstract #82754 Published in IGR 20-4
Terminology of Peters' anomaly variants: Summary of histopathological findings in 6 corneas and detailed clinicopathological correlation in 2 cases
Alkatan HM; Al Dhaheri H; Al Harby MSaudi Journal of Ophthalmology 2019; 33: 277-282
Peters' anomaly accounts for the highest type of Anterior Segment Dysgenesis (ASD). The main features of Peters' anomaly are: congenital corneal opacity centrally, defect in the posterior stroma and absence of Descemet's membrane and the endothelium. However, this condition has wide clinical and histopathological variations in appearance, associations and severity. In this case series, we summarize 6 corneas in 5 Saudi cases of Peters' anomaly (and describe 2 in detail) with unique histopathological findings that are additional to the typical known ones, shedding some light on the nomenclature of these variants according to the reported cases in the English-written literature. This will widen the spectrum of findings known to ophthalmic pathologists and ophthalmologists about this anomaly. This is also of importance in the assessment of the congenital glaucoma cases commonly seen in Saudi Arabia that often happens in association with ASD.
Departments of Ophthalmology & Pathology, College of Medicine, King Saud University Medical City, Riyadh, Saudi Arabia.
Full articleClassification:
9.1.4 Other (Part of: 9 Clinical forms of glaucomas > 9.1 Developmental glaucomas)