advertisement
PRECIS: Repeated ultrasound cyclo-plasty procedures are valuable options in patients with early or delayed intraocular pressure increase after a first procedure. The safety of a second procedure is similar to that of the first one. PURPOSE: To evaluate the efficacy and safety of repeated ultrasound cycloplasty procedures (UCP) in patients with early or delayed intraocular pressure (IOP) increase after a first procedure. PATIENTS AND METHODS: Thirty-one eyes with open-angle glaucoma, with an IOP decrease >20% after a first UCP procedure (1 and/or 2▒mo visit), and with an early or delayed IOP increase (IOP decrease <20% compared to baseline before or after the first 6▒mo, respectively) underwent a second UCP procedure. Examinations were performed at 1 day, 1 week, 1, 2, 3, 6 and 12 months. Primary outcomes were surgical success (IOP reduction ≥20% and IOP >5▒mmHg) at the last follow-up and vision-threatening complications. Secondary outcomes were mean IOP at each visit, medication use and other surgical interventions. RESULTS: In the group early IOP increase, IOP was reduced (P<0.05) from a mean value of 29.8±8.2▒mmHg before re-treatment (n=3.3 medications) to 18.5±7.4▒mmHg at the last follow-up (n=3.5 medications) (-34%). Success was achieved in 52.6% of eyes (10/19) at the last follow-up visit. In the late IOP increase group, IOP was reduced (P<0.05) from a mean value of 31.9±6.6▒mmHg before re-treatment (n=4.0 medications) to 16.2±5.2▒mmHg at the last follow-up (n=4.0 medications) (-43%). Success was achieved in 55.5% of eyes (5/9) at the last follow-up visit. No major intra- or postoperative complications occurred. CONCLUSIONS: A second UCP procedure could be considered in subjects with early or delayed failure after a first procedure.
Department of Ophthalmology, University Hospital, CHU Grenoble, Grenoble Alpes University, Grenoble, F-38043, France.
Full article12.10 Cyclodestruction (Part of: 12 Surgical treatment)