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Abstract #8320 Published in IGR 4-3
Frequency doubling technology perimetry in age-related macular degeneration
Sheu SJ; Chen YY; Chou LC; Wu TT; Cheng KKZhonghua Yi Xue Za Zhi 2002; 65: 435-440
BACKGROUND: The role of frequency doubling technology perimetry (FDT) in glaucoma is promising in terms of speed and simplicity, as well as in its high sensitivity and specificity compared to conventional automatic perimetry. In this study, the authors investigated the possible role of FDT in exudative type age-related macular degeneration (ARMD). METHODS: FDT using full-threshold C-20 mode was performed in patients with ARMD. The macula was classified into three zones by the distance from the center of the fovea (zone I: central 1°, zone II: central 3° except for zone I, zone III: central 5° except for zones I and II). The lesion was scored into three ranks by the area ratio of involvement in each zone. Retinal scores, visual acuity, and disease duration were compared with the FDT scores of the central target, which was graded into five ranks according to the probability level of abnormal points on total deviation plots using Spearsman's rank correlation method. RESULTS: Measurements from 32 eyes (30 patients) with exudative ARMD were collected. The FDT scores of the central target correlated significantly with the lesion scores in zone III (p = 0.033), but not with the lesion scores in the central 3° (zone I: p = 0.383, zone II: p = 0.077). Visual acuity was weakly correlated with the FDT scores of the central target (p = 0.022), and the lesion scores in zone III (p = 0.038), but strongly correlated with the lesion scores in zones I and II (p < 0.001). FDT scores of the central target were within normal limit in 20 eyes. CONCLUSIONS: These results suggest that FDT using full-threshold C-20 mode is not sensitive enough for the detection of small macular lesions in ARMD. Therefore, it might not be a useful functional evaluation in ARMD. Further modification of the central target of FDT is necessary to detect small macular lesions in ARMD.
S.J. Sheu, MD, Department of Ophthalmology, Kaohsiung Veterans General Hospital, 386 Ta-Chung 1st Road, Kaohsiung 813, Taiwan. sjsheu@isca.vghks.gov.tw
Classification:
6.6.3 Special methods (e.g. color, contrast, SWAP etc.) (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)