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Abstract #8366 Published in IGR 5-1
Iris color and intraocular pressure: the Blue Mountains Eye Study
Mitchell R; Rochtchina E; Lee AJ; Wang JJ; Mitchell PAmerican Journal of Ophthalmology 2003; 135: 384-386
PURPOSE: To assess the relationship between iris color and intraocular pressure (IOP). DESIGN: Population-based, cross-sectional study. METHODS: The Blue Mountains Eye Study examined 3654 largely Caucasian participants, aged 49-97 years, from 1992-1994. Information was collected about glaucoma risk factors, and Goldmann applanation IOP measurements were taken. Iris color was assessed by comparing the undilated appearance of each eye with three standard photographs. Participants who had previous cataract or glaucoma surgery and those using glaucoma medications were excluded. RESULTS: Mean IOP measurements increased with increasing grades of iris pigmentation. After simultaneous adjustment for variables associated with IOP, mean measurements were 15.92 mmHg for blue iris color, 16.04 mmHg for hazel or green, 16.11 mmHg for tan-brown, and 16.49 mmHg for dark brown (p for trend = 0.001). CONCLUSION: This study demonstrates a modest but statistically significant association between increasing iris color and IOP.
Dr. R. Mitchell, Christchurch School of Medicine, University of Otago, Christchurch, New Zealand
Classification:
1.1 Epidemiology (Part of: 1 General aspects)
