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Abstract #84554 Published in IGR 21-1
Relationship between ocular risk factors for glaucoma and optic disc rim in normal eyes
Iwase A; Sawaguchi S; Tanaka K; Tsutsumi T; Araie MBritish Journal of Ophthalmology 2020; 104: 1120-1124
AIM: To study relationships between reported risk factors for glaucoma and neuroretinal rim area in normal eyes. METHODS: The Kumejima study participants, 3762 of the 4632 eligible Kumejima residents 40 years and older, underwent a detailed ocular examination including sequential disc stereo photography. In a randomly chosen eye of a subject whose both eyes met the inclusion criteria, fundus photographs of 2474 ophthalmologically normal eyes of the 2474 subjects were analysed by computer-assisted planimetry to measure the disc, rim and β-peripapillary atrophy (PPA) areas. The rim was divided into the superior and inferior halves by a line connecting the fovea and disc centre. RESULTS: The disc, superior and inferior halves rim and β-PPA areas averaged 2.53±0.50 (SD), 0.82±0.15, 0.84±0.16 and 0.45±0.66 mm. After adjustment for other systemic and ocular factors including age, disc and β-PPA areas, disc-fovea distance (p=0.013, 0.016) correlated positively and intraocular pressure (IOP) (p=0.004, 0.006) and axial length (AL) (p<0.000, 0.004) negatively with the superior and inferior halves rim area, respectively; central corneal thickness (CCT) (p=0.008) and mean blood pressure (mBP) (p=0.020) correlated positively and male gender (p=0.012) negatively only with the superior half rims. CONCLUSIONS: Besides previously reported risk factors for glaucoma such as age or IOP, thinner CCT, lower mBP and male gender were newly found to significantly correlate with smaller rim area only in the superior half disc, and a greater disc-fovea distance with greater superior and inferior half rim areas in normal adult eyes.
Tajimi Iwase Eye Clinic, Tajimi, Gifu, Japan aiko-gif@umin.net.
Full articleClassification:
9.2.2 Other risk factors for glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
2.14 Optic disc (Part of: 2 Anatomical structures in glaucoma)
6.8.2 Posterior segment (Part of: 6 Clinical examination methods > 6.8 Photography)
