advertisement
Abstract #84639 Published in IGR 21-1
Oxidative stress and antioxidants in the trabecular meshwork
Wang M; Zheng YPeerJ 2019; 7: e8121
Glaucoma is an age-dependent disease closely related to oxidative stress and is regarded as the second leading cause of irreversible blindness worldwide. In recent years, many studies have shown that morphological and functional abnormalities of the trabecular meshwork (TM) are closely related to glaucoma, especially with respect to oxidative stress. In this review, the mechanisms of oxidative stress in the TM and treatment strategies for this condition, including strategies involving antioxidants, noncoding RNAs and exogenous compounds, are discussed. Although many questions remain to be answered, the reviewed findings provide insights for further research on oxidative stress alleviation in glaucoma and suggest new targets for glaucoma prevention.
Department of Ophthalmology, 2nd hospital affiliated to Jilin University, Changchun, China.
Full articleClassification:
2.5.1 Trabecular meshwork (Part of: 2 Anatomical structures in glaucoma > 2.5 Meshwork)
3.9 Pathophysiology (Part of: 3 Laboratory methods)
