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Abstract #8899 Published in IGR 5-2
Prevalence of open-angle glaucoma in Iceland: Reykjavik Eye Study
Jonasson F; Damji KF; Arnarsson A; Sverrisson T; Wang L; Sasaki H; Sasaki KEye 2003; 17: 747-753
PURPOSE: To establish the age- and sex-specific prevalence of open-angle glaucoma (OAG) subsuming pseudoexfoliation (PEX) in the city of Reykjavik. METHODS: Participants 50 years of age and older who were part of the Reykjavik Eye Study and classified as having glaucoma were divided into three categories: category 1: two or more of the following based on optic nerve stereophotograph reading: vertical cup to disc ratio (VCDR) 97.5 percentile (> 0.7), focal glaucomatous disc change, C/D asymmetry of 97.5 percentile difference between eyes (> 0.2) as well as glaucomatous visual field defect (GVFD); category 2: 99.5 percentile of VCDR (> 0.8) and 99.5% percentile difference between eyes (≥ 0.3), without a GVFD; category 3: VA& < 3/60 and IOP > 99.5 percentile or VA& < 3/60 and evidence of filtering surgery. For a glaucoma suspect, one of the following was present: VCDR > 99.5 percentile (> 0.8), focal glaucomatous disc change, C/D asymmetry of 99.5 percentile (≥ 0.3), GVFD only, IOP ≥ 23 mmHg (97.5 percentile). PEX was diagnosed by the presence of a central shield and/or a peripheral band on the anterior lens capsule. RESULTS: Of 42 persons (22 males and 20 females) with OAG, 13 (31.0%) had PEX. The minimum prevalence of OAG was 4.0% (42/1045) (95% CI 2.8-5.2) for those 50 years and older, and 10.3% (95% CI 8.5-12.2) for PEX. The prevalence of OAG increases with age (OR = 1.10/year, 95% CI 1.07-1.13, p = 0.000) and the same applies for the prevalence of PEX, OR = 1.10 (95% CI 1.07-1.12, p = 0.000). CONCLUSION: There is a 10% annual increase for both OAG and PEX in persons of 50 years and older.
Dr. F. Jonasson, Department of Ophthalmology University Hospital of Iceland, Landspitalinn, Iceland
Classification:
1.1 Epidemiology (Part of: 1 General aspects)