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Abstract #8994 Published in IGR 5-2
Effects of twice daily application of 2% dorzolamide on intraocular pressure in normal cats
Rainbow ME; Dziezyc JVeterinary Ophthalmology 2003; 6: 147-150
The effect of the topical carbonic anhydrase inhibitor, dorzolamide, on intraocular pressure (IOP) in cats was studied. IOP of both eyes of eight healthy cats was measured using applanation tonometery (Tono-Pen) during two phases: control and treatment. Both eyes were treated with 2% dorzolamide twice a day during the treatment phase. Application of dorzolamide resulted in a significant decrease in IOP over the treatment phase. By the fourth and fifth days of treatment, the mean IOP (± SD) was 9.7 (± 1.5) mmHg, whereas the mean (± SD) for the last two days of the control period was 12.2 (± 2.0) mmHg. Based on this study, dorzolamide is a potentially effective treatment for glaucoma in cats, significantly lowering IOP.
Dr. M.E. Rainbow, Department of Small Animal Clinical Sciences, Virginia-Maryland College of Veterinary Medicine, Blackburg, VA 24061, USA. mrainbow@vt.edu
Classification:
11.5.2 Topical (Part of: 11 Medical treatment > 11.5 Carbonic anhydrase inhibitors)
