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OBJECTIVE: To examine the safety and efficacy of selective laser trabeculoplasty as primary treatment for patients with open-angle glaucoma. METHODS: Forty-five eyes of 31 patients with open-angle glaucoma or ocular hypertension (intraocular pressure (IOP) ≥ 23 mmHg on two consecutive measurements) underwent selective laser trabeculoplasty as primary treatment. All patients underwent complete ophthalmic evaluation before and at intervals after treatment. This evaluation included visual acuity, slitlamp examination, ophthalmoscopy, gonioscopy, and visual field analysis. The IOP was measured one hour, one day, one week, and one, three, six, 12, 15, and 18 months postoperatively. During the follow-up period, patients were treated with topical antiglaucoma medications as required. RESULTS: Mean ± SD decreased by 7.7 ± 3.5 mmHg (30%), from 25.5 ± 2.5 to 17.9 ± 2.8 mmHg (p < 0.001). Only two eyes (4%) did not respond to selective laser trabeculoplasty, and three eyes (7%) required topical medications to control their IOP at the end of the follow-up period. Forty eyes (89%) had a decrease of 5 mmHg or more. Visual acuity, visual fields, and gonioscopic findings remained unchanged. Complications included conjunctival redness and injection within one day postoperatively in 30 eyes (67%). One hour after selective laser trabeculoplasty, an increase in IOP of more than 5 mmHg was detected in five eyes (11%), while an increase in IOP between 2 and 5 mmHg was measured in three eyes (7%). CONCLUSION: Selective laser trabeculoplasty is effective and safe as a primary treatment for patients with ocular hypertension and open-angle glaucoma.
Dr. S. Melamed, The Sam Rothberg Glaucoma Center, Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, Israel. melamed_shlomo@hotmail.com
12.4 Laser trabeculoplasty and other laser treatment of the angle (Part of: 12 Surgical treatment)