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Abstract #90368 Published in IGR 21-3
Low systemic vitamin D as a potential risk factor in primary open-angle glaucoma: a review of current evidence
Huynh B; Shah P; Sii F; Hunter D; Carnt N; White ABritish Journal of Ophthalmology 2021; 105: 595-601
Currently, intraocular pressure is the only modifiable risk factor for glaucoma; thus, identifying other modifiable determinants may have far-reaching outcomes. There has been increasing interest in vitamin D status and glaucoma pathogenesis as low vitamin D has been identified by some studies as an independent risk factor for glaucoma. Although the exact mechanism of vitamin D in glaucoma remains uncertain, there is sufficient evidence to continue research in this area. There is a potential physiological role for vitamin D as an anti-inflammatory agent in the oxidative stress-driven pathogenesis of primary open-angle glaucoma, and further studies are required to evaluate the temporal and causal relationship. Ocular vitamin D status in the tear, aqueous and vitreous fluid is a prospective gap in research.
Westmead Hospital, Westmead, Australia b.huynh@live.com.
Full articleClassification:
9.2.2 Other risk factors for glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
15 Miscellaneous
