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Abstract #9044 Published in IGR 5-2
Effects of thick tenon's capsule on primary trabeculectomy with mitomycin-C
Akarsu C; Önol M; Hasanreisoglu BActa Ophthalmologica Scandinavica 2003; 81: 237-241
PURPOSE: To investigate the effects of a thick tenon's capsule on primary trabeculectomy with adjunctive mitomycin-C. METHODS: In this prospective interventional case series of 45 consecutive uncomplicated glaucoma patients, 45 eyes with a thick tenon's capsule underwent primary trabeculectomy with intraoperative mitomycin-C (0.4 mg/ml for three minutes). Success was defined as intraocular pressure (IOP) ≤ 21 mmHg with (qualified) or without (complete) medications. RESULTS: The mean follow-up period was 22.55 months. The mean preoperative IOP and number of medications were 28.91 ± 7.06 mmHg and 1.68 ± 0.73, respectively. The postoperative IOPs and the number of medications at all intervals were significantly lower than preoperative levels (p < 0.01 for each interval). The mean IOP was 11.03 ± 3.93 mmHg (12.17 ± 4.98 mmHg) at 24 months (12 months). Kaplan-Meier survival analysis revealed a qualified success rate of 83.1% (95.6%) after 24 months (12 months). During follow-up of the 45 eyes, 38 (84.4%) developed avascular thin-walled blebs, seven eyes (15.6%) had hypotony (IOP < 6 mmHg), 14 eyes (31.1%) had a shallow anterior chamber, and one eye (2.2%) had endophthalmitis. CONCLUSIONS: The use of mitomycin-C is associated with high success rates and good IOP control even in the presence of a thick tenon's capsule. However, a thick tenon's capsule does not seem to eliminate the development of complications in eyes undergoing primary trabeculectomy with mitomycin-C.
Dr. C. Akarsu, Department of Ophthalmology, School of Medicine, Gazi University, Ankara, Turkey
Classification:
12.8.11 Complications, endophthalmitis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)