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Abstract #90608 Published in IGR 21-3
A case series of topiramate-induced angle closure crisis - an ophthalmic emergency
Gopalakrishna M; Odayappan A; Srinivasan K; Rengaraj VCephalalgia 2020; 40: 1389-1393
BACKGROUND: Topiramate is a drug commonly used by physicians. However, it has various systemic and ocular adverse effects. Bilateral angle closure crisis is a potentially blinding adverse reaction that is seldom reported in non-ophthalmic journals. OBJECTIVE: This article aims to report a case series of topiramate-induced angle closure crisis in the eyes. METHODS AND MATERIAL: Most patients presented to us with blurred vision and high intra-ocular pressure within days of starting topiramate tablet for headache. However, the attack resolved in those who presented early with prompt treatment, which included stopping topiramate. CONCLUSIONS: Physicians prescribing topiramate must be well aware of this potentially blinding adverse effect. Educating the patient about this possible side effect is important. Timely referral and treatment can prevent blindness in these individuals.
Department of Glaucoma, Aravind Eye Hospital, Pondicherry, India.
Full articleClassification:
9.3.1 Acute primary angle closure glaucoma (pupillary block) (Part of: 9 Clinical forms of glaucomas > 9.3 Primary angle closure glaucomas)
11.15 Other drugs in relation to glaucoma (Part of: 11 Medical treatment)
9.4.5.5 Other (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.5 Glaucomas associated with disorders of the retina, choroid and vitreous)