advertisement
Abstract #90765 Published in IGR 21-3
Uveitis as a Confounding Factor in Retinal Nerve Fiber Layer Analysis Using Optical Coherence Tomography
Yilmaz H; Koylu MT; Çakır BA; Küçükevcilioğlu M; Durukan AH; Bayer A; Mutlu FMOcular Immunology and Inflammation 2020; 0: 1-6
PURPOSE: To investigate the retinal nerve fiber layer thickness (RNFLT) in uveitic eyes and search for the associations with uveitis activity, etiology and location. METHODS: The files of 76 patients with uveitis and 76 controls were scanned. Associations of RNFLT were analyzed using generalized linear models. RESULTS: The RNFLT was significantly higher in patients with uveitis ( < .001). Active uveitis patients had a thicker RNFL than the controls and the patients with quiescent uveitis ( < .001). Anterior uveitis was associated with thinner RNFL in global and inferotemporal quadrant ( = .011 and 0.013, respectively). Thickening of RNFL was associated with posterior uveitis and Behçet's disease in all quadrants ( < .001) and idiopathic uveitis in the superonasal and nasal quadrants ( = .001). CONCLUSION: Active uveitis, as well as posterior uveitis and Behcet's disease-associated uveitis, is a major confounding factor in RNFL analysis and therefore detection of glaucoma.
Department of Ophthalmology, Health Sciences University, Umraniye Training and Research Hospital , Istanbul, Turkey.
Full articleClassification:
9.4.6 Glaucomas associated with inflammation, uveitis (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
2.13 Retina and retinal nerve fibre layer (Part of: 2 Anatomical structures in glaucoma)
6.9.2.2 Posterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)
