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Abstract #91057 Published in IGR 21-4
Microcatheter-Assisted Circumferential Trabeculotomy versus Conventional Trabeculotomy for the Treatment of Childhood Glaucoma: A Meta-analysis
Ling L; Ji K; Li P; Hu Z; Xing Y; Yu Y; Zhou WBioMed research international 2020; 2020: 3716859
BACKGROUND: The aim of the current meta-analysis was to compare the efficacy of microcatheter-assisted circumferential trabeculotomy (Group 1) with that of conventional trabeculotomy (Group 2) for the treatment of childhood glaucoma. METHODS: Published studies were systematically searched via the Web of Science, PubMed, Embase, and Cochrane Library databases. Odds ratios and 95% confidence intervals were calculated for dichotomous variables. Mean ± the standard deviation, mean difference, and 95% confidence intervals were calculated for continuous variables. Heterogeneity was assessed. Random effects modeling and RevMan version 5.30 were used to analyze the data. RESULTS: Five eligible studies were included in the meta-analysis. Mean postoperative intraocular pressures were significantly lower in Group 1 than in Group 2 at 3 months ( = 0.03), 6 months ( = 0.03), and 12 months ( = 0.007) postoperatively. The complete success rates were higher in Group 1 than in Group 2 at 3 months ( = 0.008), 6 months ( = 0.01), and 12 months ( = 0.004) postoperatively, as were the respective qualified success rates ( = 0.04, = 0.0007, and = 0.001). The pooled estimate indicated lower antiglaucoma medication use in Group 1, especially at 1 month postoperatively ( = 0.003). CONCLUSIONS: Microcatheter-assisted circumferential trabeculotomy resulted in excellent intraocular pressure control, higher success rates, and the utilization of less medication than conventional trabeculotomy for childhood glaucoma. Therefore, microcatheter-assisted circumferential trabeculotomy may be recommended as the initial procedure for the treatment of childhood glaucoma.
Affiliated Eye Hospital of Nanchang University, Nanchang Jiangxi, China.
Full articleClassification:
9.1.2 Juvenile glaucoma (Part of: 9 Clinical forms of glaucomas > 9.1 Developmental glaucomas)
12.9 Trabeculotomy, goniotomy (Part of: 12 Surgical treatment)
