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Abstract #91134 Published in IGR 21-4

Biomineralization of Trabecular Meshwork in Open-Angle Glaucoma

Kravchik MV; Subbot AM; Novikov IA; Antonov AA; Petrov SY; Petrov SY; Petrov SY; Petrov SY; Avetisov SE
Doklady. Biochemistry and biophysics 2020; 495: 307-310

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A new form of open-angle glaucoma has been identified, in which calcification and silicification of the trabecular meshwork is a potentially significant component of outflow obstruction. It is noted that the mineralization of this area is promoted by various disturbances in the acid-base balance in the tissue. The role of melanosomal enzymes in the initiation of the formation of mineral calcium phosphate in trabecular tissue in open-angle glaucoma is considered.

Research Institute of Eye Diseases, Moscow, Russia. kravchik.mv@gmail.com.

Full article

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Classification:

2.5.1 Trabecular meshwork (Part of: 2 Anatomical structures in glaucoma > 2.5 Meshwork)
3.9 Pathophysiology (Part of: 3 Laboratory methods)

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