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PURPOSE: To report an infectious cause of congenital pupillary-iris-lens membrane with secondary angle closure glaucoma in an infant. DESIGN: Case report. METHODS: Institutional review board exemption for this report was obtained from Institutional Ethics Committee, Aravind eye hospital, Tirunelveli. Informed consent was obtained.A 3 month old infant female presented to us with congenital pupillary-iris-lens membrane (CPILM), iris bombe and raised intraocular pressure (IOP) in the left eye. She underwent trabeculotomy and trabeculectomy along with membranectomy for the same. An aqueous tap performed a month later and was suggestive of co-existing Toxoplasma Gondii infection detected by polymerase chain reaction (PCR). RESULT: Description of the course of management of angle closure glaucoma secondary to CPILM with an associated infection. IOP reduced from 40 to 20▒mm Hg in the left eye. CONCLUSION: This condition is a rare entity of unknown aetiology with an increased risk of glaucoma and visual loss. A multidisciplinary approach is needed for the management of these eyes. Infectious associations with these membranes should be ruled out by an aqueous tap with PCR and a close post-operative follow up is mandatory.
Department of Glaucoma, Aravind Eye Hospital and Post-Graduate Institute of Ophthalmology, Tirunelveli - 627 001, Tamil Nadu, India.
Full article9.4.3.5 Other (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.3 Glaucomas associated with disorders of the iris and ciliary body)
9.1.2 Juvenile glaucoma (Part of: 9 Clinical forms of glaucomas > 9.1 Developmental glaucomas)
9.1.4 Other (Part of: 9 Clinical forms of glaucomas > 9.1 Developmental glaucomas)