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Abstract #9155 Published in IGR 5-2
Relationship between postural change of the intraocular pressure and visual field loss in primary open-angle glaucoma
Hirooka K; Shiraga FJournal of Glaucoma 2003; 12: 379-382
PURPOSE: To determine the relationship between the postural changes of the intraocular pressure (IOP) and the visual field loss in patients with primary open-angle glaucoma. METHODS: Eleven normal subjects and 11 patients with primary open-angle glaucoma were studied. IOP was measured in both the sitting and the supine positions. Visual fields were measured with automated perimetry. RESULTS: When patients moved from a sitting to supine position, IOP increased by an average of 3.1 ± 0.4 mmHg (mean ± SEM) in normal subjects and 4.0 ± 0.2 mmHg in patients with primary open-angle glaucoma. There was a significant difference between the normal subjects and patients with primary open-angle glaucoma (p = 0.049). IOP increased by 4.4 ± 0.3 mmHg (p = 0.02) in the worse eye for mean deviation and 3.6 ± 0.3 mmHg (p = 0.38) in the better eye for mean deviation. There was no significant difference in IOP in the sitting position between both groups. CONCLUSIONS: The greatest difference in IOP between the sitting and supine positions was observed in the worse eye of patients with primary open-angle glaucoma. This result suggests that damage to the optic nerve in primary open-angle glaucoma might occur when patients are asleep in the supine position.
Dr. K. Hirooka, Department of Ophthalmology, Kagawa Medical University, 1750-1 Ikenobe, Miki, Kagawa 761-0793, Japan. kazuyk@kms.ac.jp
Classification:
6.1 Intraocular pressure measurement; factors affecting IOP (Part of: 6 Clinical examination methods)