advertisement
Abstract #91675 Published in IGR 21-4
Assessing glaucoma deterioration using Spaeth/Richman contrast sensitivity test
Ichhpujani P; Singh T; Thakur S; Singh RB; Singh RB; Kumar STherapeutic advances in ophthalmology 2020; 12: 2515841420977412
PURPOSE: To assess changes in the central and peripheral contrast sensitivity in severe primary open-angle glaucoma (POAG) patients using a computer-based Spaeth/Richman contrast sensitivity test (SPARCS) over a period of 24 months. METHODS: Our pilot, observational study included 15 patients (30 eyes) with severe POAG. Visual acuity, intraocular pressure, number of anti-glaucoma drugs, visual fields, and SPARCS score were recorded at first visit and at 12 and 24 months. RESULTS: We observed changes in mean deviation (MD) from -19.37 ± 5.04 to -20.63 ± 4.07, mean pattern standard deviation (PSD) from 11.49 ± 2.61 to 11.35 ± 2.01, and mean SPARCS score from 54.97 ± 15.66 to 53.50 ± 16.42. We found no statistically significant difference between visual field parameters and SPARCS scores associated with the number or type of prescribed anti-glaucoma drugs. Spearman's correlation coefficient of SPARCS at baseline (SPARCS1) MD at baseline (MD1) was 0.274 ( = 0.142) and SPARCS1 PSD at baseline (PSD1) was -0.163 ( = 0.389). The correlation coefficient between SPARCS at 12 months (SPARCS2) MD (MD2) at the same time point was computed to be 0.391 ( = 0.03), whereas SPARCS2 PSD at 12 months was -0.212 ( = 0.262). Similarly, we found the coefficient to be 0.336 ( = 0.069) for SPARCS3 (SPARCS at 24 months) MD3 (MD at 24 months) and 0.242 ( = 0.197) for SPARCS3 PSD3 (PSD at 24 months). Correlation coefficients between SPARCS1/2, SPARCS1/3, MD1/2, MD1/3 PSD1/2, and PSD1/3 were 0.856, 0.865, 0.748, 0.722, 0.497, and 0.562, respectively ( < 0.001). MD changed by 9.46% ± 12.73%, PSD by 0.64% ± 14.03%, and average SPARCS by 3.31% ± 12.73% over 24 months. CONCLUSION: The data from our study indicate the utilitarian application of SPARCS, an inexpensive and readily available tool for monitoring functional deterioration in cases with advanced glaucomatous damage, especially in resource-poor settings. Furthermore, it is a useful and reliable alternative to the imaging modalities where retinal nerve fiber layer measurement can be erroneous in advanced cases secondary to the floor effect.
Professor, Department of Ophthalmology, Government Medical College & Hospital, Sector-32, Chandigarh 160030, India.
Full articleClassification:
6.6.3 Special methods (e.g. color, contrast, SWAP etc.) (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)
6.6.2 Automated (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)
