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Abstract #92262 Published in IGR 22-1
Validation of a portable, non-mydriatic fundus camera compared to gold standard dilated fundus examination using slit lamp biomicroscopy for assessing the optic disc for glaucoma
Upadhyaya S; Agarwal A; Rengaraj V; Srinivasan K; Newman Casey PA; Schehlein EEye 2022; 36: 441-447
PURPOSE: To evaluate the sensitivity and specificity of a portable non-mydriatic fundus camera to assess the optic disc for glaucoma. METHODS: We conducted a single-site, cross-sectional, observational, instrument validation study. Non-mydriatic fundus photographs centred at the optic disc were obtained from 276 eyes of 68 glaucoma and 70 normal patients, using a portable fundus camera (Smartscope, Optomed, Oulu, Finland). A senior Glaucoma consultant, masked to the patient's study participation, performed a gold standard dilated fundus examination to make the diagnosis of glaucoma. Following this, a mydriatic photograph was taken by a standard table-top fundus camera. All the images were digitalized and de-identified by an independent investigator and presented to two remote graders, masked to the patients, their diagnoses, and photographic modality. Based on individual disc characteristics, a diagnosis of screening positive or negative for glaucoma was made. In the end, the independent investigator re-identified the images. Sensitivity and specificity to detect glaucoma with the undilated Smartscope camera was calculated compared to dilated fundus examination. RESULTS: Grading remote images taken with the portable non-mydriatic fundus camera showed a sensitivity of 96.3% (95% confidence interval (CI): 91.6-98.8%) and 94.8% (95% CI: 89.7-97.9%) and a specificity of 98.5% (95% CI: 94.9-99.8%) and 97.8% (95% CI: 93.9-99.6%) for the two graders respectively as compared to gold standard dilated fundus examination. CONCLUSION: The non-mydriatic Smartscope fundus images have high sensitivity and specificity for diagnosing glaucoma remotely and thus may be an effective tool for use in community outreach programs.
Aravind Eye Hospital and Post Graduate Institute of Ophthalmology, Pondicherry, India. swati.dr@aravind.org.
Full articleClassification:
6.8.2 Posterior segment (Part of: 6 Clinical examination methods > 6.8 Photography)
6.3.2 Posterior segment (Part of: 6 Clinical examination methods > 6.3 Biomicroscopy (slitlamp))