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WGA Rescources

Abstract #92373 Published in IGR 22-1

Investigating the Relationship between Glaucoma Prevalence and Trabecular Meshwork Length

Choi W; Cho H; Kim EW; Bae HW; Kim CY; Seong GJ
Journal of clinical medicine 2021; 10:


Glaucoma is one of the most common causes of blindness worldwide, but the risk factors of glaucoma are yet to be fully understood. We investigated the relationship between the prevalence of glaucoma and trabecular meshwork (TM) length by comparing the mean TM length of a South Korean population with that of another ethnic population. We included 250 eyes of 125 patients who underwent anterior segment optical coherence tomography at Yonsei University Gangnam Severance Hospital between January 2015 and December 2017. We measured the distance from the scleral spur to Schwalbe's line in patients with open and closed angles and calculated the TM length using the open- and closed-angle ratios in the general population. The mean TM length of the patients in our study was 752 ± 116 μm. Considering the compensated data, the estimated true mean TM length in the Korean population was 793 ± 76 μm, which was similar to the mean TM length of a previously evaluated Hispanic population, but differed significantly from those of previously evaluated Asian (Chinese), Caucasian, and African-American populations ( < 0.05). Our results support the hypothesis that the development of glaucoma would be affected by TM length.

Institute of Vision Research, Department of Ophthalmology, College of Medicine, Yonsei University, Seoul 03722, Korea.

Full article

Classification:

1.1 Epidemiology (Part of: 1 General aspects)
2.5.1 Trabecular meshwork (Part of: 2 Anatomical structures in glaucoma > 2.5 Meshwork)
6.9.2.1 Anterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)



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