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Abstract #92560 Published in IGR 22-1
Comparison of the Prevalence and Clinical Characteristics of Epiretinal Membrane in Pseudoexfoliation and Primary Open Angle Glaucoma
Lee JY; Sung KR; Kim YJJournal of Glaucoma 2021; 0:
PURPOSE: To investigate and compare the prevalence and clinical characteristics of epiretinal membrane (ERM) in patients with pseudoexfoliation glaucoma (PXG) and primary open angle glaucoma (POAG). METHODS: In this retrospective observational study, 211 PXG eyes, age matched 210 normal and 220 POAG eyes were included. The presence and staging of ERM (stage 1, 2, and 3 or greater) were independently assessed by two observers. Univariate and multivariate linear regression analyses were performed to assess the factors associated with visual field (VF) mean deviation (MD) in PXG eyes. RESULTS: Among 211 PXG eyes, 40 (19.0%) had an ERM, while 4.1% of POAG and 2.4% of normal eyes had an ERM (P<0.001). Retinal nerve fiber layer (RNFL) thickness (69.4 vs. 70.4▒μm, P=0.477) and VF MD (-7.7 vs. -10.4▒dB, P=0.098) were not different between POAG and PXG eyes but macular thickness was greater (259.5 vs. 271.5▒μm, P=0.006) in PXG eyes than in POAG. Both lower RNFL thickness (β=0.337, P <0.001) and the presence of an ERM (β=-4.246, P = 0.002) were independently associated with worse VF MD in PXG eyes. CONCLUSIONS: The prevalence of ERM was significantly greater in PXG eyes than in age matched normal or POAG eyes. The presence of ERM affected visual field in PXG eyes.
Department of Ophthalmology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea.
Full articleClassification:
9.4.4.1 Exfoliation syndrome (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.4 Glaucomas associated with disorders of the lens)
9.4.5.5 Other (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.5 Glaucomas associated with disorders of the retina, choroid and vitreous)
2.13 Retina and retinal nerve fibre layer (Part of: 2 Anatomical structures in glaucoma)
